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Carboxymethylcellulose Calcium

Carboxymethylcellulose Calcium

Carboxymethylcellulose Calcium

INCI Name: Carboxymethylcellulose Calcium

Chemical Name: Calcium Carboxymethylcellulose, CMC-Ca, ECG505

CAS No. :  9050-04-8

Carboxymethyl cellulose calcium is a disintegrant with adhesive properties. Typical dosage: 0.5-5.0%, the highest dosage can reach 15%.

More details


Carboxymethylcellulose Calcium

 

INCI Name: Carboxymethylcellulose Calcium

Chemical Name: Calcium Carboxymethylcellulose, CMC-Ca, ECG505

 

CAS No. :  9050-04-8

EINECS No. :  618-566-8

 

Molecular Formula: C23H30ClN3O

Molecular Weight: 399.95

 

Specification:

Items

Specification

1. Appearance:

White to yellowish-white powder

2. Identification:

(1)   A red-purple color develops

(2)   A white, flocculent precipitate is produced

(3)   A blue, flocculent precipitate is produced

(4)   The solution responds to the tests for calcium

3. Chloride:

0.3 max

4. Sulfate:

1.0 max

5. Loss on drying %:

10.0 max

6. Residue on ignition %:

10.0 - 20.0

7. Heavy metals(as Pb)ppm:

20 max

8. Acidity:

No red color develops

9. pH:

4.5 – 6.0

10. Particle size:

90% through 200mesh

11. General Bacteria (CFU/g):

100 max

 

Application: Carboxymethyl cellulose calcium is a disintegrant with adhesive properties. Has the ability to quickly absorb water and expand. It is suitable for wet granulation and powder direct pressing process; it has good compressibility, and because of its good chelating structure, it has good dissolution improvement performance for cephalosporins. Because of its calcium salt, it is particularly suitable for cardiovascular drugs that limit sodium salt. Typical dosage: 0.5-5.0%, the highest dosage can reach 15%.

 

Package:  10kg per carton /20kg per carton.

 

Storage: Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.

 

Shelf Life: 3 years.